A Connection Found Between Hidradenitis Suppurativa and Bipolar Disorder

By Rob Dillard - Last Updated: December 21, 2022

People with hidradenitis suppurativa (HS) are more likely to have bipolar disorder (BD), according to a study published in Dermatology Practical & Conceptual.

Researchers of this study sought to discern the prevalence of BD among HS patients and present the HS and BD overlap patients’ demographics, detailed clinical characteristics with a discussion on aggravating factors. They conducted a retrospective review of 247 HS patients (Group 1), of which nine were identified with BD. The investigators then compared the frequency of BD in HS patients to the same frequency in psoriasis patients (Group 2), and controls (Group 3).

According to the results, BD was the 7th most common co-morbidity in the HS cohort, equating to a frequency of 3.6%. The frequencies were found to be notably lower in group 2 at 0.7%, and 0.6%in group 3, respectively. The researchers noted that in HS and BD co-existence, 66.6% were active smokers, 66.6% were obese and 44.4 % had metabolic syndrome.

“This study results reveal that the prevalence of BD in HS patients is higher than psoriasis patients and controls. The pathogenetic mechanisms underlying BD and HS co-existence needs to be investigated further,” the researchers concluded.

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