Study Highlights Gender Disparities in Psoriatic Arthritis

By Rob Dillard - Last Updated: April 12, 2023

Psoriatic arthritis (PsA) is a heterogeneous disease with notable clinicobiological differences between men and women, according to a recent study published in the Journal of Clinical and Translational Research.

This retrospective, observational, single-center study comprised of 132 patients from the rheumatology department of Amiens University Hospital with a confirmed diagnosis of PsA.

According to the results, the disparities between men and women are multiple and consistent with the literature. The findings showed that the polyarticular form, enthesitis, obesity, more intensive prescription of s-DMARDs, and b-DMARDs are more commonly linked with women. Oligoarticular form, psoriatic nail dystrophy, radiological axial involvement, and chronic hyperuricemia are more commonly correlated with men.

“Our study found a very heterogeneous disease, with marked differences between men and women. Peripheral PsA remains predominant but the search for associated axial involvement, which is probably underestimated, seems essential,” the researchers concluded.

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