Tamara Thomas

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Young adult cancer survivors are at higher risk of heart failure when treated with anthracyclines. According to a study published in <a href="https://www.jacc.org/doi/10.1016/j.jaccao.2023.03.009" target="_blank" rel="noopener">JACC: Cardio Oncology</a>, this chemotherapy drug damages DNA in cancer cells.
Previous studies show cardiovascular disease is the leading cause of death in cancer survivors. However, there is limited data on heart failure (HF) risk among young adult cancer survivors.
Elizabeth Hibler, PhD, MPH, and colleagues at Northwestern University, Evanston, Illinois, conducted a study to evaluate the association between cancer diagnosis and the risk of HF among young adults. The study involved 12,879 young adult cancer survivors aged 18-39 at diagnosis and treated with anthracyclines.
The researchers observed that young adult cancer survivors had more than 2 times the risk of HF when treated with anthracyclines. They also observed that the occurrence of HF was the highest for cancer survivors of leukemia.
Furthermore, the research team observed that kidney, lymphoma, bone, and breast cancer survivors had a higher incidence of HF than study participants diagnosed with other types of cancer and were more likely to be treated with anthracyclines.
&#8220;Thankfully, people are increasingly surviving early-onset cancer, but once they do, they&#8217;re at risk of long-term side effects, like heart failure and infertility,&#8221; said Dr. Hibler.
&#8220;What we&#8217;re trying to do is apply our findings to studying other cancer medications to try to understand if they impact the heart,&#8221; Dr. Hibler stated. She continued, &#8220;Our goal is to improve early detection because there are early treatments for heart failure if the patient is showing signs.&#8221;
The researchers call for future studies to further understand if newer types of cancer treatment can also increase the risk of HF, even for young people.
Source: <a href="https://medicalxpress.com/news/2023-05-young-cancer-survivors-higher-premature.html" target="_blank" rel="noopener">MedicalXpress</a>

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Young Cancer Survivors Face an Increased Risk of Premature Heart Failure

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Young adult cancer survivors are at higher risk of heart failure when treated with anthracyclines. 

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