Chronic Spontaneous Urticaria
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Acupuncture therapy as an adjunct to omalizumab was found to improve disease control and quality of life.
Patients with CSU who utilized a digital telehealth platform reported improved quality-of-life scores.
Urticaria raises the risk of ADHD, bipolar disorder, and schizophrenia.
Omalizumab is a safe and effective long-term treatment for CSU.
Nearly 50% of patients with chronic spontaneous urticaria are atopic, with atopy linked to increased risk of dermatographism,
A recent study demonstrated significant associations between acute urticaria and cardiovascular comorbidities.
Autoimmune mast cell activation test shows promise as a diagnostic tool for chronic spontaneous urticaria.
Omalizumab treatment in CSU patients leads to significant changes in T-cell subpopulations.
Patients with both asthma and chronic urticaria have more severe allergic responses.
Omalizumab effectively reduces symptoms in CSU patients, but a 300 mg dose is recommended.
A systematic review found that biologic omalizumab is cost-effective for treating H1 antihistamine–refractory CSU.
According to a recent study, serum zonulin levels had a significant correlation with the urticaria activity score
Eosinophil/neutrophil/platelet/basophil-to-lymphocyte ratios did not significantly change during 6 months of omalizumab.
Autologous serum skin test status positivity, comorbid allergic diseases are associated with early response to omalizumab.
Omalizumab updosing is commonly needed within the first 3 months of treatment for patients with severe CSU.
Stem cell factor expression was significantly elevated in both the lesional and nonlesional skin of patients with CSU.
Elevated serum orexin-A levels are associated with poorer sleep quality in patients with chronic spontaneous urticaria.
Low total immunoglobin E levels, high systemic inflammation response are predictors of poor response to omalizumab.
A recent study showed positive anti-thyroid peroxidase is a significant risk factor for acute urticaria progression.
Patients with chronic inducible urticaria respond well to antihistamines and omalizumab.
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