Disparities in Sickle Cell Disease

Pediatric Sickle Cell Complications Spike in Colder Climates, New Study Finds
In a newly published study in Pediatric Blood & Cancer, researchers report a notable association between colder weather and increased rates of vaso-occlusive episodes (VOEs) and acute chest syndrome (ACS) in children with sickle cell disease (SCD). Drawing on data from the Pediatric Health Information System (PHIS) and the National Climatic Data Center from 2015 to 2022, the team identified more than 84,000 events, most of which were VOEs. Not only did these complications peak in January through March, but specific weather variables played distinct roles: VOE admissions correlated positively with wind speed and snowfall yet dropped as average temperatures rose, whereas ACS hospitalizations ...
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March 29, 2025

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