Tamara Thomas

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Women with celiac disease had a higher overall rate of experiencing women&#8217;s health disorders like ovarian dysfunction, irregular menstruation, and infertility, amongst others, according to a study presented at the American College of Gastroenterology Annual Scientific Meeting.
Previous studies have suggested a link between celiac disease and delayed menarche as well as early menopause in women. However, research on the specific impact of celiac disease on women&#8217;s reproductive health, particularly in North America, remains limited.
For their study, Dr. Rama Nanah, a clinical hospitalist at Cleveland Clinic, and colleagues evaluated nationwide data of about 9368 women with celiac disease compared with 25 million women without the disease. The study participants were predominately white (83% vs. 47%).
According to the results presented at the scientific meeting, women living with celiac disease had significantly higher odds of primary ovarian failure (0.96% vs. 0.16%), which included both ovarian dysfunction and polycystic ovarian syndrome.
&#8220;Our study found higher overall rates of women&#8217;s health disorders in women with celiac disease compared to nonceliac at all hormonal stages of life,&#8221; Dr. Nanah said.
The researchers also noted that women with celiac disease were more likely to experience irregular menstruation (15.5% vs. 6.9%), dysmenorrhea (10.9% vs. 4.24%), menopause and perimenopausal disorder (4.3% vs. 1.56%), endometriosis (2.3% vs. 0.93%), infertility (1.44% vs. 0.85%), and absent or rare menstruation (4.6% vs 2%).
The researchers call for clinicians to be more aware of the association between celiac disease and women&#8217;s health. This increased awareness should include screening for CD in women with these conditions and detecting the presence of these women&#8217;s health disorders in CD patients during routine or follow-up care.
&#8220;By raising awareness of these higher rates of women&#8217;s health disorders in women with celiac disease, we hope this will provide a call to gastroenterologists to think of this association and evaluate patients accordingly, including referral to and partnership with our OB/GYN colleagues to care for these women,&#8221; Dr.Nanah told Healio. &#8220;Early diagnosis and management are crucial for these patients to minimize complications and take advantage of their fertile lifespan should they be interested in a family,&#8221; she concluded.
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Source: <a href="https://www.healio.com/news/gastroenterology/20231025/higher-overall-rates-of-womens-health-disorders-reported-among-those-with-celiac-disease">Healio</a>
Journal:<a href="https://journals.lww.com/ajg/fulltext/2023/10001/s1792_women_s_health_disorders_in_a_celiac_disease.2133.aspx"> Americal College of Gastroenterology Annual Scientific Meeting</a>

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Women with celiac disease had a higher overall rate of experiencing women's health disorders like ovarian dysfunction, irregular menstruation, and infertility.

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