The prognosis for induction failure in childhood T-cell ALL remains unfavorable despite advancements in treatment. Being overweight or obese was associated with increased toxicity and higher nonrelapse mortality. Sociodemographic factors lead to disparities in outcomes for multiple myeloma patients. Researchers discovered that breast cancer survivors had a heightened risk of being diagnosed with pericarditis. The insurance status of patients with AML impacted access to molecular genetic sequencing and overall survival. Children with ALL living in extreme poverty had a significantly higher risk of relapse during maintenance therapy. Age, marital status, and tumor site were independent prognostic factors for extramedullary multiple myeloma. BMI before and at MM diagnosis did not significantly impact survival. Black patients with CLL received less targeted therapy compared with White patients. An educational intervention increased provider confidence in aligning multiple myeloma treatment decisions. Black patients with CLL have later diagnoses, shorter overall survival, and more advanced disease at diagnosis. Patients with multiple myeloma who are treated at academic centers have significantly improved survival rates. Despite overall improved survival rates, racial and ethnic disparities in survival persist, according to a recent study.
... Treatment facility type and volume affect overall survival and therapy utilization in MM patients. Metabolically unhealthy normal weight and obesity were associated with increased risk of adverse outcomes. Being obese or underweight is linked to a worse prognosis among people with multiple myeloma. Diabetes is associated with an increased risk of developing overall and site-specific cancers. Low-income Black/Hispanic patients with acute leukemia reported financial concerns and difficulty making appointments. Black patients with Hodgkin Lymphoma had worse rates of overall survival. Screening for residual disease before a bone marrow transplant may help physicians identify which adult patients may relapse.