Lockdown measures enacted during the COVID-19 pandemic may have accelerated brain aging in females faster than imagined. Studies have found that having both ovaries removed before natural menopause increases the risk of cognitive impairment. Black women with good heart health showed little decline in mental processing. Suicide rate among Black women increased rapidly from 1999 to 2020, especially among Black teens and young adults. Women experiencing earlier menopause and higher vascular risk had lower cognitive scores. According to a survey, in states with trigger laws banning abortions, women reported a rise in anxiety and depression. Cognitive function in middle age is a strong predictor of whether a person may develop dementia later in life. Racial discrimination is linked with lower subjective cognitive function (SCF) among African American women.